The potential of Phenibut – Smart Drug or Curse ?!

March 18th, 2020

Introduction of Phenibut:

Also known as “4-Amino-3-Phenylbutyric Acid,” sold under the brand names Anvifen, Fenibut, and Noofen among others is a central nervous system depressant with anxiolytic effects.  It was synthesized in the 1960s in Russia where it is licensed for use in anxiety, depression, attention deficit disorder, post-traumatic stress disorder, and other health issues. Phenibut is a non-prescription pharmaceutical that is actually a GABA molecule with the addition of a phenyl group. Russian researchers discovered that by changing GABA into 4-Amino-3-Phenylbutyric Acid, it was able to cross more easily into the nervous system & across the blood-brain barrier. Since it is a GABA, an inhibitory neurotransmitter, derivative, Phenibut increases GABA levels.

Phenibut is a white crystalline powder and the taste is very sour. It is readily soluble in water, soluble in alcohol, and the pH of a 2.5% water solution is between about 2.3 and 2.7.

 Good points of Function:

  •  Phenibut is a derivative of the naturally occurring inhibitory neurotransmitter GABA.
  •  Phenibut is used by bodybuilders to reduce fatigue and improve neurological functions.
  •  Phenibut is used to treat stress disorder.
  •  Phenibut relieves tension, improves sleep, treat fear, sleep problems,  fatigue, post-traumatic depression.

Abuse of Phenibut:

Some of the common side abusing effects of phenibut :
  • Phenibut can make sedation, nausea, anxiety, dizziness, and headache.
  • Higher doses of Phenibut can make coordination problems like loss of balance.
  • Physical and psychological withdrawal symptoms include decreased appetite, depression, cognitive deficit, fatigue, dizziness, palpitations.


CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on the Web. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.